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Pneumovax is a vaccine for prevention of disease caused by strains of Neisseria meningitidis.

A) True
B) False

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Streptococcal pharyngitis involves all the following, except


A) a purulent exudate over the tonsils.
B) can lead to scarlet fever if it is an erythrogenic toxin-producing strain.
C) can lead to serious sequelae.
D) is usually caused by the viridans streptococci.
E) causes redness, difficulty in swallowing, and fever.

F) C) and D)
G) A) and C)

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An individual with asymptomatic N. gonorrhoeae may not spread the disease.

A) True
B) False

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All of the following are correct about Streptococcus pyogenes, except


A) humans are the only significant reservoir.
B) some of the streptococcal toxins act as superantigens.
C) most strains do not have a capsule.
D) it can cause impetigo and erysipelas.
E) infection is generally through direct contact.

F) D) and E)
G) B) and E)

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Having received no prenatal care, a young woman arrives at a hospital after many hours of labor and delivers a baby girl. Three days later the baby girl is listless, nursing poorly, and is running a fever. Blood cultures are done, and after 24 hours, they are Gram stained and show the presence of gram-positive cocci in pairs and short chains. Upon subculture, these form colonies that are beta hemolytic on blood agar. Further tests demonstrate that the isolate is catalase negative, resistant to bacitracin, and is CAMP test positive. What is the identification of this organism?


A) Streptococcus pyogenes
B) Streptococcus pneumoniae
C) Streptococcus agalactiae
D) Staphylococcus aureus
E) Neisseria meningitidis

F) C) and E)
G) None of the above

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In which of the following situations would Staphylococcus epidermidis be the most likely etiologic agent?


A) otitis media
B) food intoxication
C) urinary bladder infection
D) infected IV catheter site
E) conjunctivitis

F) B) and D)
G) C) and D)

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Streptococcus pyogenes causes all the following, except


A) necrotizing fasciitis.
B) erysipelas.
C) impetigo.
D) scarlet fever.
E) scalded skin syndrome.

F) None of the above
G) B) and E)

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Which organism is associated with commonly causing urinary tract infections in sexually active young adult and adolescent females?


A) Staphylococcus aureus
B) Staphylococcus epidermidis
C) Staphylococcus saprophyticus
D) Streptococcus pyogenes
E) Streptococcus agalactiae

F) B) and E)
G) C) and D)

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The most common site where carriers of Staphylococcus aureus carry this pathogen is


A) all over the skin.
B) under the fingernails.
C) anterior nares nostrils) .
D) mouth.
E) intestines.

F) A) and E)
G) A) and C)

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Symptoms of Toxic Shock Syndrome include all the following, except


A) fever and muscle pain.
B) appearance of flesh being "eaten" down to the muscle.
C) nausea, vomiting and diarrhea.
D) sunburn-like rash.
E) kidney and liver failure.

F) A) and C)
G) B) and D)

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All the following pertain to Staphylococcus epidermidis infections, except


A) they often develop from an endogenous source.
B) they typically occur after insertion of shunts and prosthetic devices.
C) catheterization can introduce the organism and lead to urinary tract infection.
D) the organism is coagulase negative.
E) the organism produces a large number of tissue damaging enzymes and toxins.

F) All of the above
G) B) and C)

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Local Staphylococcus aureus infections often involve formation of an abscess.

A) True
B) False

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The enzyme that coagulates pla is


A) catalase.
B) coagulase.
C) hyaluronidase.
D) staphylokinase.
E) Dnase.

F) C) and E)
G) None of the above

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The two important hemolysins of Group A streptococci are _____ and _____.

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streptolys...

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Sue brought her daughter Amy to the pediatrician complaining of a sore throat. The physician examines Amy and observes that her throat is bright red and there are white pus-filled nodules on her tonsils. Which of the following conclusions should be made?


A) She has a strep throat and should begin antibiotics.
B) She should have a rapid strep test performed before a diagnosis is made.
C) She should go home and rest because most sore throats are viral in origin.
D) She should go home and come back in two days for a strep test since it may take that long to show up.
E) She has a staphylococcal sore throat and should begin antibiotics immediately.

F) A) and B)
G) B) and E)

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An 8-month old infant has been brought to the ER with a high fever. Her parents indicate that she has not been eating or drinking well and has been very irritable until the last few hours during which she has been only minimally responsive. Suspecting meningitis, a spinal tap is done and the CSF sample is sent to the lab for analysis. The white blood cell count on the sample is profoundly elevated, the protein content is elevated, and the glucose level is depressed. The Gram stained smear shows gram-positive cocci in pairs. Cultures are done and after overnight incubation, alpha hemolytic colonies are observed on the blood plate. These colonies contain gram-positive cocci, which are catalase negative. An optochin susceptibility test is done and there is a large zone of inhibition around the disk. What is the identification of this isolate?


A) Streptococcus pneumoniae
B) viridans Streptococci
C) Enterococcus faecalis
D) Neisseria meningitidis
E) Streptococcus agalactiae

F) A) and C)
G) C) and D)

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List three enzymes and four toxins produced by Staphylococcus aureus. For each enzyme and toxin, discuss its effect on patient tissues and how it contributes to virulence of this pathogen.

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Three enzymes produced by Staphylococcus...

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Neisseria meningitidis and Neisseria gonorrhoeae are fastidious, gram-negative cocci that produce oxidase.

A) True
B) False

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The viridans streptococci are


A) not entirely groupable by Lancefield serology.
B) the most numerous residents of the oral cavity.
C) opportunists that can cause subacute endocarditis.
D) introduced to deeper body tissues by dental or surgical procedures.
E) All of these choices are correct.

F) A) and C)
G) None of the above

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All of the following are correct about Staphylococcus aureus, except


A) it is the coagulase-positive species.
B) the body's most powerful defense against it lies in the T-cell response.
C) carriers may be treated with antibiotics to clear them of the bacteria.
D) most strains are resistant to penicillin and ampicillin.
E) it causes furuncles, carbuncles, and abscesses.

F) B) and E)
G) C) and D)

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